He will be a serious loss to his family.

All this would amount to a serious financial loss for the company.

By doing this the house would risk having to write off its already very serious losses.

The dead on the floor told him that his own men had suffered serious losses.

The problem with the move is that it could result in a serious loss of income for the company.

But the distances are so great there would be no serious loss of life.

Right after a serious loss or difficult life change (the death of someone close, a stressful move).

It suffered a serious loss of foreign investment as a result.

My death, let me tell you, would mean a serious financial loss to her.

If they both go, it is a very serious loss at the top of our foreign service.