I believe we can hand his army a major defeat.

It was the first major legislative defeat of Clinton's administration.

But that didn't happen after the last major Republican defeat in 1992.

But what seemed like a major legal defeat was an important political victory.

They suffered a major defeat at their hands in 1819.

Instead, the tactic lead to a major defeat for labor.

He suffered a major defeat and was killed on the spot.

His one major defeat was on a proposal for state health insurance.

The battle was the first major defeat of the war for the Americans, and it came at a high price.

It was also this country's first major defeat in battle.