There is evidence suggesting corneal collagen cross-linking may be beneficial for patients with pellucid marginal degeneration.

Hersh has done extensive work on corneal collagen cross-linking (CXL), a procedure for decreasing the progression of keratoconus and corneal ectasic disorders, and he has published numerous articles in ophthalmology medical journals analyzing the results of the use of this procedure for keratoconus and ectasia.