chromosome aberration

Some of the genes and chromosome aberrations affect behaviour in selective ways.

They are easy to analyze compared to chromosome aberrations.

However, the results of several in vitro studies, including chromosome aberration tests in human lymphocytes, are positive.

Oocytes with premature anaphase, polyploidy, or structural chromosome aberrations were not found.

Chromosome aberration was discovered and she received a dose of anticancer medicine from the United States to treat it.

Mycoplasmas may induce cellular changes, including chromosome aberrations, changes in metabolism and cell growth.

Chromosomal Triplication None Trisomies are very rare genetic disorders characterized by a chromosome aberration.

He maintains a database of all published chromosome aberrations in neoplastic disorders, with clinical features, now numbering more than 57,000 cases (as of November 2009).

This technique is used to identify structural chromosome aberrations in cancer cells and other disease conditions when Giemsa banding or other techniques are not accurate enough.

This is similar to the micronucleus test and chromosome aberration assay, which detect structural and numerical chromosomal aberrations in mammalian cells.

The result of another study showed that aqueous extracts reduced mitotic index, but induced chromosome aberrations and mitotic aberrations in comparison with control, significantly.

On the basis of current coefficients, however, one cannot assume that calculation of individual exposure doses resulting from fallout would not induce measurable rates of chromosome aberrations.

Use of BAC clone CTD-3193o13 as a FISH probe in the analysis of chromosome aberrations associated with developmental abnormalities.

While this process seems quite simple and repetitive, defects in Okazaki fragment maturation can cause DNA strand breakage which can cause varying forms of "chromosome aberrations".

This method allows one to identify new recurrent chromosome changes such as microdeletions and duplications in human conditions such as cancer and birth defects due to chromosome aberrations.

"Renal and Urinary Tract Abnormalities Associated with Chromosome Aberrations," International Journal of Pediatric Nephrology 8: 215, 1987.

People living in the polluted air of a large city in Poland have more adducts and chromosome aberrations than people living in the cleaner air of a Polish village.

Additionally the method can be used to detect numerical chromosome aberrations in archival pathology samples and so represents an alternative to the use of FISH assays that require specialized microscopy.

Bloomfield CD, Archer KJ, Mrózek K, et al.: 11q23 balanced chromosome aberrations in treatment-related myelodysplastic syndromes and acute leukemia: report from an international workshop.

Liou SH, Lung JC, Chen YH, et al.: Increased chromosome-type chromosome aberration frequencies as biomarkers of cancer risk in a blackfoot endemic area.

The BAC clones which contain chromosome aberrations will have end sequences that do not map to a similar region of reference genome, thus identifying a chromosomal breakpoint present in cancerous genomes.

When identified in prenatal ultrasound, it is considered statistically correlated with increased risk of chromosome aberration in the fetus and may be an indication for intrauterine sampling for fetal chromosome analysis.

Cytogenetic Models Resource The Jackson Laboratory Cytogenetic Models Resource maintains and distributes chromosome aberration stocks that provide primarily mouse models for Down syndrome.

The Mitelman Database of Chromosome Aberrations in Cancer also contains information on the molecular genetic and clinical consequences of cancer-associated chromosome aberrations.

In 1938 Karl Sax published a paper entitled "Chromosome Aberrations Induced by X-rays," which demonstrated that radiation could induce major genetic changes by affecting Chromosomal translocations, a chromosome abnormality.