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It is situated at the bottom of a micropylar cup which lies between the anchor filaments.
Attached to the lymphatic capillaries are anchoring filaments, which contain elastic fibers.
Anchoring filaments traverse the lamina lucida space and appear to insert into the electron dense zone, the lamina densa.
Together with the anchoring fibrils and anchoring filaments, these are collectively termed the HD-stable adhesion complex or HD-anchoring filament complex.
When excess interstitial fluid accumulates and causes tissue swelling, the anchoring filaments are pulled, making the openings between cells even larger so that more fluid can flow into the lymphatic capillary.
Due to the primarily amorphous fibrous and nonfibrous proteins in lamina propria (LPs), the basement membrane applies strong anchoring filaments like collagenⅣ and Ⅶ to secure the hemidesmosome of basal cell to LPs.
The basal cells in the stratum basale of the epidermis connect to the basement membrane by the anchoring filaments of hemidesmosomes; the cells of the papillary layer of the dermis are attached to the basement membrane by anchoring fibrils, which consist of type VII collagen.
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