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It can be used in the alveolar gas equation.
Figures 6show the corresponding fits for the alveolar gas concentration.
The alveolar air equation is the following formula, used to calculate the partial pressure of alveolar gas:
Free interactive model of the simplified and complete versions of the alveolar gas equation (AGE)
The alveolar gas equation allows the calculation of the alveolar partial pressure of oxygen from data that is practically measurable.
Online Alveolar Gas Equation and iPhone application by Medfixation.
Gas exchange occurs in the pulmonary alveoli by passive diffusion of gases between the alveolar gas and the blood in lung capillaries.
The alveolar pO is not routinely measured but is calculated from blood gas measurements by the Alveolar gas equation.
In normal respiratory control, negative feedback allows a steady level of alveolar gas concentrations to be maintained, and therefore stable tissue levels of oxygen and carbon dioxide (CO).
Lung diseases that primarily cause abnormality in alveolar gas exchange usually do not cause hypoventilation but tend to cause stimulation of ventilation and hypocapnia secondary to hypoxia.
In the oxygen-rich capillaries of the lung, this property causes the displacement of carbon dioxide to plasma as low-oxygen blood enters the alveolus and is vital for alveolar gas exchange.
It is assumed in the PBPK model that the arterial blood and alveolar gas partial pressures are equal and correspond to the experimentally measured end tidal gas partial pressure.
Deeper or quicker breaths as in hyperventilation exchange more of the alveolar gas with ambient air and have the net effect of expelling more carbon dioxide from the body, since the carbon dioxide concentration in normal air is very low.
This is because although the PO2 of alveolar gas has been changed by giving pure supplemental O2, the PaO2 ( Arterial gas pressure ) will not increase that much because the V/Q mismatch still exists and it will still add some de-oxygenated blood to the arterial system via the shunt.
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