Adult-onset Still's disease

Adult-onset Still's Disease is rare and has been described all over the world.

One set of 21 adult-onset Still's disease patients were divided into four types, according to clinical course patterns.

Adult-onset Still's disease is treated with anti-inflammatory drugs.

Adult-onset Still's disease is a systemic inflammatory disease.

A multicenter study of patients with adult-onset Still's disease compared with systemic juvenile idiopathic arthritis.

It is sometimes called "adolescent-onset Still's disease", to distinguish it from adult-onset Still's disease.

The adult disease is now more commonly called adult-onset Still's disease (AOSD).

E. G. L. Bywaters characterises adult-onset Still's disease, a rare form of inflammatory arthritis.

The cause of adult-onset Still's disease is not known, but it presumably involves IL-1, since drugs that block the action of IL-1β are effective treatments.

Adult-onset Still's disease, some porphyrias, and hemophagocytic lymphohistiocytosis/macrophage activation syndrome are diseases in which the ferritin level may be abnormally raised.

Patients experiencing a flare-up from Adult-onset Still's disease usually report extreme fatigue, swelling of the lymph glands, and less commonly fluid accumulation in the lungs and heart.

Anders Lindbäck was diagnosed with Adult-onset Still's disease months before he entered the 2008 NHL Draft which made him get drafted so late despite his excellence.

A 2005 article published in Arthritis & Rheumatism reported rapid improvement in four patients with Adult-Onset Still's Disease who were treated with Anakinra.

In addition, MAS has been described in association with systemic lupus erythematosus (SLE), Kawasaki disease, and adult-onset Still's disease.

Authors of a 2012 review article published in the International Journal of Inflammation concluded that "a growing number of evidences supports the utilisation of anakinra in Adult-Onset Still's Disease".

Inflammatory arthritis is a group of diseases which includes: rheumatoid arthritis, psoriatic arthropathy, inflammatory bowel disease, adult-onset Still's disease, scleroderma, juvenile idiopathic arthritis and systemic lupus erythematosus (SLE).

These include (and are not limited to) auto-immune or -inflammatory disorders such as adult-onset Still's disease, angioedema, hematological disorders such as lymphoma or monoclonal gammopathy of undetermined significance, other causes of hives, cryoglobulinemia, mastocytosis, chronic neonatal onset multisystem inflammatory disease or Muckle-Wells syndrome.